Najdekr Lukáš Ph.D.
O mně
My area of research was always within the grasp of the metabolomics field. After I studied biochemistry, I have been working at the University Hospital Olomouc and my PhD was focused on medical genetics – especially in the potential application of untargeted metabolomics tools in clinical practice as a diagnostic tool. During my first internship at the University of Barcelona (Barcelona, Spain) I have learnt how to work with cell cultures and various techniques in molecular biology. During my second internship in San Jose (CA, USA) at Thermo Fisher Scientific, I got advanced skills and training in Orbitrap-based mass spectrometers and software. I see the metabolomics great potential as a ‘universal’ diagnostic tool in personalised medicine. In my opinion, the first signs can already be seen e.g. as use of the iKnife or in the improvement in new-born screening across the world. As a part of a great team of the scientists of Phenome Centre Birmingham, I was able to participate in many projects which helped me to get deeper insights in cooperation between academia and commercial subjects (industry). Now I have returned to my alma mater to the Palacký University where I want to continue my research. In future, I would like to focus my efforts on the study of the oxidative stress on the metabolite level. I would like to transfer more of lipidomics research into clinical practice. In my opinion, lipidomics approach has a great diagnostic potential for clinicians and there are still many undiscovered research opportunities.
Journals
Master mentorship
Pokorná Natálie
Development and validation of LC/MS assay for analyses of fat-soluble vitamins
Bachelor mentorship
Machálková Markéta
Untargeted metabolomics of T-lymphoblastic leukemia cells affected by quinolinone derivative
Šťastná Veronika
Metabolomic analysis of mouse plasma using aminopropyl column and TripleQ-MS
Mádrová Lucie M.Sc
Analysis of lipids in blood stains for the diagnosis of inherited metabolic disorders
Open positions
| Projekt: | Use of open-source software approaches for analysis of metabolomic and lipidomic clinical data |
|---|---|
| Vedoucí: | Najdekr Lukáš Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Projekt: | Isolation and analysis of membrane lipid rafts using a non-targeted metabolomics and lipidomics approach |
|---|---|
| Vedoucí: | Najdekr Lukáš Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |